About NRI

Institute Leadership

Texas Children's Hospital is already home to scientists recognized for their revolutionary work in genetics and neurology. The Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital will build on this strength and the visionary leadership of Drs. Huda Zoghbi, John Swann, and the late Dr. Ralph D. Feigin.

Huda Y. Zoghbi, M.D., Director

Ralph D. Feigin, M.D., Endowed Chair

Professor, Departments of Pediatrics, Molecular and Human Genetics, Neurology, and Neuroscience, Baylor College of Medicine

Investigator, Howard Hughes Medical Institute

Member, Institute of Medicine and National Academy of Sciences

"We will use research in the true sense of multidisciplinary research as a tool to eventually get treatments in patients. Whether they are childhood or adult neurodegenerative diseases, they can be reversed if we can figure out how to intervene."  

Internationally renowned scientist Dr. Huda Zoghbi serves as director of the Jan and Dan Duncan Neurological Research Institute. Dr. Zoghbi first made headlines when she co-discovered the gene that causes spinocerebellar ataxia type 1, a crippling neurological disease. She and her team then discovered that mutations in MeCP2 cause the neurodevelopmental disease Rett syndrome, an autism spectrum disorder.

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John W. Swann, Ph.D., Co-Director

Scientific Director, Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories, Texas Children's Hospital

Professor, Departments of Pediatrics and Neurosciences, Baylor College of Medicine

Former President, American Epilepsy Society

"Pediatric neurological diseases are bigger than any one lab. They are bigger than any one investigator. It's going to take a team."  

Dr. John W. Swann is the Co-director, Jan and Dan Duncan Neurological Research Institute and the scientific director of Texas Children's Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories, where clinicians and research scientists are focused on understanding and ultimately curing the causes of childhood seizure disorders. Dr. Swann has shown that intractable focal seizures are related to problems in the early growth and migration of neurons. With the help of developmental neurobiologists and bioinformaticians, Dr. Swann's laboratory is working on identifying the molecules that could correct these errors.

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